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Request free EDS demo software at

EDS is exclusively distributed in Europe on Delica TCD systems

Shenzhen, China.

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 #1.SOLID & ARTEFACT   (TIA&Stroke)













EDS     Mission

To spread the insight to the medical community that

the smart use of cerebral embolus detection software will prevent strokes in all patients with an increased stroke risk.


We will achieve this mission by:


1.  Releasing free EDS demo's that teach you how solid en gaseous emboli look like under different clinical conditions.

2. Providing the medical community the best software to detect solid and gaseous emboli in TCD recordings.

3.  Providing teaching files with different types of

solid & gaseous emboli and artifacts in the bloodstream.


4. Providing lectures on stroke prevention by TCD embolus detection.

5. Free review and feedback your own TCD audio-files.


Additional TCD Stroke Prevention Initiatives 
developed by R.W.M. Keunen MD PhD

The Haga Braincare Strategy

The Haga Braincare Stragey has been developed to reduce the burden of focal and global ischemia related to cardiac surgery. It is a dual strategy in which patients with cerebral flow states are identified prior to surgery by TCD Ultrasound and in which patients are monitored per--operatively by non-invasive NIRS cerebral oximetry. In a retrospective follow-up study we noticed a the Haga Teaching Hospital an extinction of postoperative hemodynamic strokes and a > 50 % reduction of the post operative delirium...

Prevention of Malignant Cerebral Hyperfusion after Carotid Surgery or Angioplasthy

Cerebral hyperperfusion syndromes are reperfusion syndromes that may occur in the run off MCA territory after stenting or surgery of high grade ipsilateral carotid artery stenosis. Most of these hyperperfusion syndromes are transient phenomena with no residual brain lesions. However some of them result in a devastating hemorrhagic stroke. The main risk factors  of such a devastating stroke is when systemic hypertension and failed cerebral auto regulation interact with each other. Implementing intelligent TCD and RR management in these patients may prevent such devastating strokes...

Current EDS     research
Inspirators of the EDS     development

  Merrill Spencer               Rune Aaslid        Rob Ackerstaff          Run

EDS     Achievements
  • 2007 Programmer Remco Hoogenboezem & vascular neurologist Ruud Keunen designed the first zero-crossing based  embolus detection algorithm for discrimination for single solid emboli and artefacts from TCD audio recordings.

  • 2008 EDS has been CE certified, published and brought to the European Market.

  • 2009 Antonius Nieuwegein and University Medical Centre Utrecht amongst the first centres in  Holland which started to monitor carotid surgery  with EDS.

  • 2015 Over 10 Dutch Vascular Medical Centres uses over 15 EDS systems mainly to monitor carotid surgery  

  • 2020 EDS is exclusively distributed on Delica TCD systems with a focus to serve European Medical Centres

  • 2021 EDS was presented in over 20 lectures and zoom meetings over Europe

  • 2022 Invited EDS lecture at University of Cambridge for Peter Smielewski and Marik Czosnyka

  • 2022 Semmelweis University Budapest is the 10th European Medical Centre that uses the EDS software to monitor Pulmonary Vene Isolation

  • 2022 EDS Medical and the Deventer hospital start a cooperation to validated the EDS  PFO algorithm to detect gaseous emboli in TCD recordings.

  • 2022 EDS presented a new Solild/Gaseous/Artefact Algorithm at the 22th ESNCH Meeting in Lisbon

  • 2023 EDS lectures at the Karolinska University Stockholm and University of Orebro Sweden

  • 2023 TU Delft and EDS Medical sign a  contract for better understanding mathematics of micro-embolic signals of TCD recordings.


The EDS is a premium CE certified software for detecting solid and gaseous emboli in the bloodstream. The EDS has been developed and validated by Dr. RWM Keunen, a Dutch neurologist working at the Haga Teaching Hosipitals, The Hague, The Netherlands.


Embolus detection is a unique diagnostic tool to identify patients with an increased stroke risk.


EDS is applied in the management of (a)symptomatic carotid artery stenosis, peri-operative monitoring of patients scheduled for carotid, cardiac, TAVI and PVI procedures

EDS    Universities
Christian Doppler Uni, Salzburg, Austria
Karolinska Hospital, Stockholm, Sweden

Zurich University Hospital Switzerland

Semmelweis Budapest Hungary

Debrecen University Debrecen Hungary

Rostock University RostockGermany

Inselspital Bern Switzerland

Erasmus Rotterdam The Netherlands

UMCU Utrecht The Netherlands

UMC Groningen The Netherlands

UMC Maastricht The Netherlands

University of Kaunas Letland

Umea University Hospital Sweden

University of Wurzburg, Germany

EDS    Hospitals

HagaZiekenhuis Den Haag, The Netherlands

Antonius Nieuwegein, The Netherlands

Elisabeth Tilburg, The Netherlands

Isala Klinieken, Zwolle. The Netherlands

Ziekenhuis Deventer, The Netherlands

Franciscus Rotterdam, The Netherlands

Catharina Eindhoven, The Netherlands

Dijklander Hoorn, The Netherlands

Marien Hospital Bottrop, Germany

Klinikum Esslingen, Germany

Klinikum Schaumburg, Germany

Kaposvár Hospital, Hungary

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EDS       Delica  Distributors

Cardio Solutions BV
Landsmeer The Netherlands
for the Benelux countries

SMT Medical GmbH&Co. KG
Würzburg Germany
for the DACH countries

DHS Hungary Ltd.
Budapest Hungary

Disclosures Dr. Keunen

Dr. Keunen was vascular neurologist at the Haga Hospital from 1990-2020. Since 2021 Dr. Keunen is research neurologist at the department of cardiosurgery at the Haga Hospitals the Hague The Netherlands and owner of EDS Medical Softeware BV.

Dr. Keunen is medical advisor of Medtronic Trading NL BV The Netherlands. Delica China, SMT Medical Germany, Cardio Solutions The Netherlands and DHS Hungary

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